Entity Central Index Key
Warrants down round feature increase decrease in equity amount.
Cover [Abstract]
Entity Registrant Name
Entity Registrant Name
Entity Central Index Key
Entity Central Index Key
Current Fiscal Year End Date
Current Fiscal Year End Date
Entity Well-known Seasoned Issuer
Entity Well Known Seasoned Issuer
Entity Voluntary Filers
Entity Voluntary Filers
Entity Current Reporting Status
Entity Current Reporting Status
Entity Filer Category
Entity Filer Category
Document Annual Report
Document Annual Report
Document Transition Report
Document Transition Report
Entity Small Business
Entity Small Business
Entity Emerging Growth Company
Entity Emerging Growth Company
Entity Ex Transition Period
Entity Ex Transition Period
Entity Incorporation, State or Country Code
Entity Incorporation State Country Code
Entity Interactive Data Current
Entity Interactive Data Current
Entity File Number
Entity File Number
Entity Tax Identification Number
Entity Tax Identification Number
Entity Address, Address Line One
Entity Address Address Line1
Entity Address Address Line2
Entity Address Address Line2
Entity Address City Or Town
Entity Address City Or Town
Entity Address State Or Province
Entity Address State Or Province
Entity Address Postal Zip Code
Entity Address Postal Zip Code
City Area Code
City Area Code
Local Phone Number
Local Phone Number
Entity Shell Company
Entity Shell Company
Entity Public Float
Entity Public Float
Entity Common Stock, Shares Outstanding
Entity Common Stock Shares Outstanding
Document Fiscal Year Focus
Document Fiscal Year Focus
Trading Symbol
Trading Symbol
Title of 12(b) Security
Security12b Title
Document Fiscal Period Focus
Document Fiscal Period Focus
Document Type
Document Type
Amendment Flag
Amendment Flag
Document Period End Date
Document Period End Date
ICFR Auditor Attestation Flag
Icfr Auditor Attestation Flag
Security Exchange Name
Security Exchange Name
Statement Of Financial Position [Abstract]
Assets
Assets [Abstract]
Current assets
Assets Current [Abstract]
Cash and cash equivalents
Cash And Cash Equivalents At Carrying Value
Restricted cash
Restricted Cash And Cash Equivalents At Carrying Value
Accounts receivables, net
Accounts Receivable Net Current
Inventories
Inventory Net
Prepaid expenses and other current assets
Prepaid Expense And Other Assets Current
Total current assets
Assets Current
Property, plant and equipment, net
Property Plant And Equipment Net
Right-of-use assets
Operating Lease Right Of Use Asset
Total assets
Assets
Liabilities and Stockholders' Equity (Deficit)
Liabilities And Stockholders Equity [Abstract]
Current liabilities
Liabilities Current [Abstract]
Accounts payable
Accounts Payable Current
Accrued expenses
Accrued Liabilities Current
Deferred revenue, current
Deferred Revenue Current
Lease liabilities, current
Operating Lease Liability Current
Convertible notes payable, current
Convertible Notes Payable Current
Warrant liability
Derivative Liabilities Current
Total current liabilities
Liabilities Current
Deferred revenue, non-current
Deferred Revenue Noncurrent
Lease liabilities, non-current
Operating Lease Liability Noncurrent
Convertible notes payable, non-current
Convertible Long Term Notes Payable
Total liabilities
Liabilities
Commitments and contingencies (Note 13)
Commitments And Contingencies
Stockholders' Equity (Deficit)
Stockholders Equity [Abstract]
Preferred stock, $.01 par value; 10,000,000 shares authorized; 20,631 and 41,517 shares issued and outstanding at December 31, 2020 and December 31, 2019, respectively
Preferred Stock Value
Common stock, $.01 par value; 40,000,000 and 1,000,000,000 shares authorized; 5,996,101 and 67,091 shares issued and outstanding at December 31, 2020 and December 31, 2019, respectively*
Common Stock Value
Additional paid-in capital
Additional Paid In Capital
Accumulated deficit
Retained Earnings Accumulated Deficit
Accumulated other comprehensive (loss) income
Accumulated Other Comprehensive Income Loss Net Of Tax
Total stockholders' equity (deficit)
Stockholders Equity
Total liabilities and stockholders' equity (deficit)
Liabilities And Stockholders Equity
Preferred stock, par value (in dollars per share)
Preferred Stock Par Or Stated Value Per Share
Preferred stock, shares authorized (in shares)
Preferred Stock Shares Authorized
Preferred stock, shares issued (in shares)
Preferred Stock Shares Issued
Preferred stock, shares outstanding (in shares)
Preferred Stock Shares Outstanding
Common stock, par value (in dollars per share)
Common Stock Par Or Stated Value Per Share
Common stock, shares authorized (in shares)
Common Stock Shares Authorized
Common stock, shares issued (in shares)
Common Stock Shares Issued
Common stock, shares outstanding (in shares)
Common Stock Shares Outstanding
Income Statement [Abstract]
Statement [Table]
Statement [Table]
Product and Service
Product Or Service [Axis]
Product and Service
Products And Services [Domain]
Product Revenue [Member]
Product [Member]
Other Revenue [Member]
Product And Service Other [Member]
Statement [Line Items]
Statement [Line Items]
Revenue
Revenue From Contract With Customer Excluding Assessed Tax
Cost of goods sold
Cost Of Revenue
Gross profit
Gross Profit
Operating expenses:
Operating Expenses [Abstract]
Research and development expenses
Research And Development Expense
Selling, general and administrative expenses
Selling General And Administrative Expense
Total operating expenses
Operating Expenses
Operating loss
Operating Income Loss
Change in fair value of the warrant liability, net
Fair Value Adjustment Of Warrants
Loss on issuance of financial instrument
Amortization Of Financing Costs
Interest expense
Interest Income Expense Nonoperating Net
Other income
Other Nonoperating Income
Net loss
Net Income Loss
Deemed dividend for triggering of warrant down round feature
Warrants Down Round Feature Increase Decrease In Equity Amount
Net loss attributable to common stockholders
Net Income Loss Attributable To Noncontrolling Interest
Net loss
Other comprehensive (loss) income:
Other Comprehensive Income Loss Net Of Tax Period Increase Decrease [Abstract]
Foreign currency translation adjustments
Other Comprehensive Income Loss Foreign Currency Transaction And Translation Adjustment Net Of Tax
Total other comprehensive loss
Comprehensive Income Net Of Tax
Common share data:
Earnings Per Share Basic And Diluted [Abstract]
Basic loss per common share*
Earnings Per Share Basic
Diluted loss per common share*
Earnings Per Share Diluted
Weighted average number of basic shares outstanding*
Weighted Average Number Of Shares Outstanding Basic
Weighted average number of diluted shares outstanding*
Weighted Average Number Of Diluted Shares Outstanding
Reverse stock split
Stockholders Equity Note Stock Split
Reverse stock split ratio
Stockholders Equity Note Stock Split Conversion Ratio1
Shares settled for accrued compensation shares.
Shares settled for accrued compensation value.
Adjustment to additional paid in capital registration of preferred stock and related warrants
Adjustments to additional paid In capital fair value of warrants reclassified from liability to equity.
Stock issued during period value exercise of warrants for common stock shares
Stock issued during period value exercise of warrants for common stock
Issuance of common stock and warrants in public offering shares.
Issuance of common stock and warrants in public offering.
ATM Offering Shares,
ATM Offering,
Issuance of common stock confidentially marketed public offering shares
Issuance of common stock confidentially marketed public offering
Stock issued during period, value, exercise of pre-funded warrants.
Stock issued during period value exchange of warrants for common stock.
Statement Of Stockholders Equity [Abstract]
Equity Components
Statement Equity Components [Axis]
Equity Component
Equity Component [Domain]
Common Stock [Member]
Common Stock [Member]
Preferred Stock [Member]
Preferred Stock [Member]
Additional Paid in Capital [Member]
Additional Paid In Capital [Member]
Accumulated Deficit [Member]
Retained Earnings [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Other Comprehensive Income [Member]
Class of Stock
Statement Class Of Stock [Axis]
Class of Stock
Class Of Stock [Domain]
Series D Preferred Stock [Member]
Series D Preferred Stock [Member]
Series E Preferred Stock [Member]
Series E Preferred Stock [Member]
Series e1 preferred stock member
Series E1 Preferred Stock [Member]
Series E1 Preferred Stock [Member]
Class of Warrant or Right
Class Of Warrant Or Right [Axis]
Class of Warrant or Right
Class Of Warrant Or Right [Domain]
Series D warrants.
Series D Warrants
Series D Warrants [Member]
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Increase Decrease In Stockholders Equity Roll Forward
Balance
Balance (in shares)
Shares Outstanding
Compensation expense for issuance of stock options
Adjustments To Additional Paid In Capital Share Based Compensation Stock Options Requisite Service Period Recognition
Compensation expense for issuance of restricted stock
Stock Issued During Period Value Restricted Stock Award Net Of Forfeitures
Compensation expense for issuance of restricted stock (in shares)
Stock Issued During Period Shares Restricted Stock Award Net Of Forfeitures
Shares settled for services
Stock Issued During Period Value Issued For Services
Shares settled for services (in shares)
Stock Issued During Period Shares Issued For Services
Shares settled for accrued compensation
Shares Settled For Accrued Compensation Value
Shares settled for accrued compensation (in shares)
Shares Settled For Accrued Compensation Shares
Issuance of Preferred Stock
Adjustments To Additional Paid In Capital Stock Issued Issuance Costs
Stock issued during period, shares.
Issuance of Preferred Stock (in shares)
Stock Issued During Period Shares
Retirement of Series D Preferred Stock
Stock Repurchased And Retired During Period Value
Retirement of Series D Preferred Stock (in Shares)
Stock Repurchased And Retired During Period Shares
Exercise of Pre-Funded Series D Warrants
Stock Issued During Period Value Exercise Of Pre Funded Warrants
Stock issued during period, shares, Exercise of pre-funded warrants.
Exercise of pre-funded warrants (in shares)
Stock Issued During Period Shares Exercise Of Pre Funded Warrants
Exchange of warrants
Stock Issued During Period Value Exchange Of Warrants For Common Stock
Stock issued during period shares exchange of warrants for common stock.
Exchange of warrants (in shares)
Stock Issued During Period Shares Exchange Of Warrants For Common Stock
Fair value of warrants issued
Adjustments To Additional Paid In Capital Warrant Issued
Conversion of preferred stock into common stock
Stock Issued During Period Value Conversion Of Convertible Securities
Conversion of Preferred stock into common stock (in shares)
Stock Issued During Period Shares Conversion Of Convertible Securities
Registration costs of Series E and Series E-1 Preferred Stock and related warrants
Adjustment To Additional Paid In Capital Registration Of Preferred Stock And Related Warrants
Fair value of warrants reclassified from liability to equity
Adjustments To Additional Paid In Capital Fair Value Of Warrants Reclassified From Liability To Equity
Exercise of warrants into common stock
Stock Issued During Period Value Exercise Of Warrants For Common Stock
Exercise of warrants into common stock (in shares)
Stock Issued During Period Value Exercise Of Warrants For Common Stock Shares
Public Offering - issuance of common stock and warrants
Issuance Of Common Stock And Warrants In Public Offering
Public Offering - issuance of common stock and warrants (in shares)
Issuance Of Common Stock And Warrants In Public Offering Shares
ATM Offering
A T M Offering
ATM Offering, Shares
A T M Offering Shares
Confidentially Marketed Public Offering - issuance of common stock
Issuance Of Common Stock Confidentially Marketed Public Offering
Confidentially Marketed Public Offering - issuance of common stock (in shares)
Issuance Of Common Stock Confidentially Marketed Public Offering Shares
Fractional rounding related to reverse stock split
Adjustments To Additional Paid In Capital Stock Split
Fractional rounding related to reverse stock split (in shares)
Stock Issued During Period Shares Reverse Stock Splits
Comprehensive loss
Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent
Balance
Balance (in shares)
It represents as a gross proceeds of public offering.
Statement Of Cash Flows [Abstract]
Sale of Stock
Subsidiary Sale Of Stock [Axis]
Sale of Stock
Sale Of Stock Name Of Transaction [Domain]
At the Market Offering.
At-the-Market Offering [Member]
At Market Offering [Member]
Gross proceeds
Gross Proceeds Of Public Offering
Issuance costs
Payments Of Stock Issuance Costs
Stock option compensation (income) expense.
Restricted stock compensation (income) expense.
Amortization of right of use assets.
Interest income earned on money market and operating accounts.
Equitization of expenses.
Loss on issuance of financial instruments.
Reclassification of warrants from liability to equity.
Non cash activities fair value of warrants issued.
Issuance of restricted stock for 2019 bonuses due to executive officers.
Series E and E-1 preferred stock and warrants member.
Series E and E-1 Preferred Stock and Warrants [member]
Series E And E1 Preferred Stock And Warrants [Member]
IPO [Member]
I P O [Member]
First sale of stock by a private company to the public.
IPO 2 [Member]
I P O2 [Member]
Cash flows from operating activities:
Net Cash Provided By Used In Operating Activities [Abstract]
Net loss
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract]
Stock option compensation expense
Stock Option Compensation Income Expense
Restricted stock compensation expense
Restricted Stock Compensation Income Expense
Depreciation expense
Depreciation
Amortization of right of use assets
Amortization Of Right Of Use Assets
Warrant liability fair value adjustment
Non-cash interest income
Interest Income Earned On Money Market And Operating Accounts
Equitization of expenses
Equitization Of Expenses
Loss on issuance of financial instruments
Loss On Issuance Of Financial Instruments
Interest expense accrued related to convertible notes
Paid In Kind Interest
Debt discount amortization
Amortization Of Debt Discount Premium
Changes in assets and liabilities:
Increase Decrease In Operating Capital [Abstract]
Increase in prepaid expenses and other assets
Increase Decrease In Prepaid Deferred Expense And Other Assets
(Increase) decrease in accounts receivable
Increase Decrease In Accounts Receivable
(Increase) decrease in inventories
Increase Decrease In Inventories
Decrease in accounts payable and accrued expenses
Increase Decrease In Accounts Payable And Accrued Liabilities
Decrease in deferred revenue
Increase Decrease In Contract With Customer Liability
Decrease in other liabilities
Increase Decrease In Other Operating Liabilities
Net cash used in operating activities
Net Cash Provided By Used In Operating Activities
Cash flows from investing activities:
Net Cash Provided By Used In Investing Activities [Abstract]
Purchase of property, plant and equipment
Payments To Acquire Property Plant And Equipment
Net cash used in investing activities
Net Cash Provided By Used In Investing Activities
Cash flows from financing activities:
Net Cash Provided By Used In Financing Activities [Abstract]
Net proceeds from the issuance of debt
Proceeds From Issuance Of Debt
Net proceeds from the sale of Series E and E-1 Preferred Stock and warrants
Proceeds From Issuance Of Preferred Stock And Preference Stock
Principal payments of financing leases
Finance Lease Principal Payments
Net payments related to reverse stock split
Payments Of Capital Distribution
Fees paid related to preferred stock conversions
Proceeds on Public Offering (1)
Proceeds From Issuance Initial Public Offering
Proceeds on ATM Offering Trades (2)
Proceeds From Issuance Or Sale Of Equity
Proceeds from exercise of warrants
Proceeds From Warrant Exercises
Net cash provided by financing activities
Net Cash Provided By Used In Financing Activities
Foreign currency effects on cash, cash equivalents and restricted cash
Effect Of Exchange Rate On Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
Net increase in cash, cash equivalents and restricted cash
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
Cash, cash equivalents and restricted cash:
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations [Abstract]
Beginning of year
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
End of year
Supplemental Disclosure of Cash Flow Information:
Supplemental Cash Flow Information [Abstract]
Interest expense
Interest Paid Net
Supplemental Disclosure of Non-Cash Investing and Financing Activities:
Noncash Investing And Financing Items [Abstract]
Conversions of preferred stock into common stock
Conversion Of Stock Amount Issued1
Reclassification of 2019 warrants from liability to equity
Reclassification Of Warrants From Liability To Equity
Equitization of debt, interest and expenses into July 2019 Private Placement
Stock Issued1
Fair value of warrants issued
Non Cash Activities Fair Value Of Warrants Issued
Adoption of ASC 842 lease standard
Capital Lease Obligations Incurred
Right of use assets obtained in exchange for lease obligations
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
Financing of D&O insurance premium
Proceeds From Payments For Other Financing Activities
Issuance of restricted stock for 2019 bonuses due to executive officers
Issuance Of Restricted Stock For2019 Bonuses Due To Executive Officers
Documents Incorporated by Reference
Documents Incorporated By Reference [Text Block]
Organization Consolidation And Presentation Of Financial Statements [Abstract]
Description of Business
Business Description And Basis Of Presentation [Text Block]
Basis of condensed consolidated financial statement presentation.
Basis Of Condensed Consolidated Financial Statement Presentation [Abstract]
Basis of Consolidated Financial Statement Presentation
Basis Of Accounting
Accounting Policies [Abstract]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Cash And Cash Equivalents [Abstract]
Cash, Cash Equivalents and Restricted Cash
Cash And Cash Equivalents Disclosure [Text Block]
Inventory Disclosure [Abstract]
Inventories
Inventory Disclosure [Text Block]
Prepaid expenses and other current assets.
Deferred Costs Capitalized Prepaid And Other Assets Disclosure [Abstract]
Prepaid Expenses And Other Current Assets
Prepaid Expenses And Other Current Assets [Text Block]
Property Plant And Equipment [Abstract]
Property, Plant, and Equipment
Property Plant And Equipment Disclosure [Text Block]
Payables And Accruals [Abstract]
Accrued Expenses
Accounts Payable And Accrued Liabilities Disclosure [Text Block]
Lessee operating and finance leases.
Leases [Abstract]
Leases
Lessee Operating And Finance Leases [Text Block]
Debt Disclosure [Abstract]
Convertible Notes Payable
Debt Disclosure [Text Block]
Stockholders Equity Note [Abstract]
Stockholders' Equity
Stockholders Equity Note Disclosure [Text Block]
Fair Value Disclosures [Abstract]
Fair Value Measurements
Fair Value Disclosures [Text Block]
Commitments and Contingencies Disclosure [Abstract]
Commitments
Commitments Disclosure [Text Block]
Income Tax Disclosure [Abstract]
Income Taxes
Income Tax Disclosure [Text Block]
Subsequent Events [Abstract]
Subsequent Events
Subsequent Events [Text Block]
Risk and uncertainties.
Risk and Uncertainties
Risk And Uncertainties Policy [Text Block]
Liquidity and going concern.
Liquidity and Going Concern
Liquidity And Going Concern Policy [Text Block]
Use of Estimates
Use Of Estimates
Cash Equivalents and Concentrations of Credit Risk
Cash And Cash Equivalents Policy [Text Block]
Restricted Cash
Cash And Cash Equivalents Restricted Cash And Cash Equivalents Policy
Accounts Receivable
Trade And Other Accounts Receivable Policy
Inventories
Inventory Policy [Text Block]
Property, Plant and Equipment
Property Plant And Equipment Policy [Text Block]
Derivative Instrument Liability
Derivatives Policy [Text Block]
Fair Value Measurements
Fair Value Measurement Policy Policy [Text Block]
Revenue Recognition
Revenue Recognition Policy [Text Block]
Contract with customer liability.
Deferred Revenue
Contract With Customer Liability Policy [Text Block]
Selling, General and Administrative
Selling General And Administrative Expenses Policy [Text Block]
Research and Development
Research And Development Expense Policy
Stock Based Compensation
Share Based Compensation Option And Incentive Plans Policy
Income Taxes
Income Tax Policy [Text Block]
Net Loss per Common Share
Earnings Per Share Policy [Text Block]
Segment Information
Segment Reporting Policy Policy [Text Block]
Foreign Currency and Currency Translation
Foreign Currency Transactions And Translations Policy [Text Block]
Reclassification of Prior Year Presentation.
Reclassification of Prior Year Presentation
Reclassification Of Prior Year Presentation Policy [Text Block]
Recently issued Accounting Pronouncements and Accounting Standards to be Adopted
New Accounting Pronouncements Policy Policy [Text Block]
Anti-dilutive securities excluded from the computation of earnings per share
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block]
Schedule of Cash, Cash Equivalents, and Restricted Cash
Schedule Of Restricted Cash And Cash Equivalents [Text Block]
Schedule of inventories
Schedule Of Inventory Current Table [Text Block]
Prepaid Expenses and Other Current Assets
Deferred Costs Capitalized Prepaid And Other Assets Disclosure [Text Block]
Components of property, plant and equipment
Property Plant And Equipment [Text Block]
Schedule of current accrued expenses
Schedule Of Accrued Liabilities Table [Text Block]
Schedule of operating and financing leases.
Summary of Operating and Financing Leases
Schedule Of Operating And Financing Leases Table [Text Block]
Schedule of Maturity of Operating Leases Excluding Short-Term Leases
Lessee Operating Lease Liability Maturity Table [Text Block]
Summary of Various Notes Issued
Convertible Debt Table [Text Block]
Schedule of Assumptions to Estimate Fair Value of Stock Options Using Black-Scholes Option Pricing Model
Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block]
Summary of Stock Option Activity
Schedule Of Stock Options Roll Forward Table [Text Block]
Summary of Stock Option Shares Outstanding and Exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding And Exercisable Table [Text Block]
Summary of Recognized Share-based Compensation Cost
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block]
Summary of Warrant Activity
Schedule Of Stockholders Equity Note Warrants Or Rights [Text Block]
Schedule of Information Related to Stock Warrants Outstanding and Exercisable.
Schedule of Information Related to Stock Warrants Outstanding and Exercisable
Schedule Of Information Related To Stock Warrants Outstanding And Exercisable Table [Text Block]
Fair value measurements using significant unobservable inputs
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation [Text Block]
Schedule of fair value of the outstanding warrants
Schedule Of Assumptions For Fair Value As Of Balance Sheet Date Of Interests Continued To Be Held By Transferor Servicing Assets Or Servicing Liabilities [Text Block]
Assets and liabilities measured at fair value on a recurring basis
Schedule Of Fair Value Assets And Liabilities Measured On Recurring Basis Table [Text Block]
Schedule of future minimum lease payments, net of receipts due under terms of subleases under all operating leases
Schedule Of Future Minimum Rental Payments For Operating Leases Table [Text Block]
Schedule of Loss Before Income Taxes
Schedule Of Income Before Income Tax Domestic And Foreign Table [Text Block]
Income Tax Reconciliation
Schedule Of Effective Income Tax Rate Reconciliation Table [Text Block]
Significant Components of Deferred Tax Assets
Schedule Of Deferred Tax Assets And Liabilities Table [Text Block]
Summary of Change in Valuation
Summary Of Valuation Allowance [Text Block]
Net loss
Net cash used in operating activities
The entity considers investments with original maturities of certain months or less at the date of acquisition to be cash equivalents.
Summary of significant accounting policies.
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Statistical Measurement
Range [Axis]
Statistical Measurement
Range [Member]
Minimum [Member]
Minimum [Member]
Maximum [Member]
Maximum [Member]
Hedging Designation
Hedging Designation [Axis]
Hedging Designation
Hedging Designation [Domain]
Designated as Hedges [Member]
Designated As Hedging Instrument [Member]
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Maximum period of investments with original maturities from date of acquisition to be cash equivalents
Maximum Period Of Investments With Original Maturities From Date Of Acquisition To Be Cash Equivalents
Property, plant and equipment, estimated useful life
Property Plant And Equipment Useful Life
Number of derivative instruments
Derivative Number Of Instruments Held
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Securities
Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis]
Antidilutive Securities, Name
Antidilutive Securities Name [Domain]
Common stock warrants equity member.
Common Stock Warrants - Equity [Member]
Common Stock Warrants Equity [Member]
Common stock warrants liability member.
Common Stock Warrants - Liability [Member]
Common Stock Warrants Liability [Member]
Assumed conversion of Series E and E-1 Preferred Stock.
Assumed Conversion of Series E and Series E-1 Preferred Stock [Member]
Assumed Conversion Of Series E And E1 Preferred Stock [Member]
Assumed conversion of convertible notes.
Assumed Conversion of Convertible Notes [Member]
Assumed Conversion Of Convertible Notes [Member]
Stock Options [Member]
Employee Stock Option [Member]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive securities excluded from computation of earnings per share (in shares)
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
Letters of credit restricted cash.
Security for credit cards restricted cash.
Letters of credit
Letters Of Credit Restricted Cash
Security for credit cards
Security For Credit Cards Restricted Cash
Total cash, cash equivalents and restricted cash shown in the statement of cash flows
Raw materials
Inventory Raw Materials
Work-in-process
Inventory Work In Process
Total Inventory
Prepaid clinical trial expenses current.
Prepaid Expense And Other Assets Current [Abstract]
Clinical trial expenses
Prepaid Clinical Trial Expenses Current
Insurance premiums
Prepaid Insurance
Other
Other Prepaid Expense Current
Total prepaid expenses and other current assets
Maximum percentage of various prepaid expenses and other current assets to the aggregate prepaid expenses and other current assets.
Maximum percentage of prepaid expenses and other current assets (in hundredths)
Maximum Percentage Of Prepaid Expenses And Other Current Assets
Schedule Of Property Plant And Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Long-Lived Tangible Asset
Property Plant And Equipment By Type [Axis]
Long-Lived Tangible Asset
Property Plant And Equipment Type [Domain]
Buildings and Land [Member]
Land Buildings And Improvements [Member]
Enterprise Hardware and Software [Member]
Computer Equipment [Member]
Leaseholds [Member]
Leaseholds And Leasehold Improvements [Member]
Equipment [Member]
Equipment [Member]
Furniture [Member]
Furniture And Fixtures [Member]
Buildings [Member]
Building [Member]
Property Plant And Equipment [Line Items]
Property Plant And Equipment [Line Items]
Property, plant and equipment, gross
Property Plant And Equipment Gross
Accumulated depreciation
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
Property, plant, and equipment, net
Property, plant and equipment, estimated useful life
Property, plant and equipment, estimated useful life
Property Plant And Equipment Estimated Useful Lives
Exercised option to purchase.
Exercised option to purchase
Exercised Option To Purchase
Accrued clinical trial expenses current.
Clinical trial expenses
Accrued Clinical Trial Expenses Current
Compensation, excluding taxes
Employee Related Liabilities Current
Other
Other Accrued Liabilities Current
Total accrued expenses
Maximum percentage of various single other accrued expenses to the aggregate current liabilities.
Maximum percentage of current liabilities accrued (in hundredths)
Maximum Percentage Of Current Liabilities Accrued
Lease term
Lessee Operating Lease Term Of Contract
Financing lease cost.
Finance lease principal payment on liability.
Operating lease and financing lease weighted average remaining lease term.
Other lease information.
Lessee Lease Description [Table]
Lessee Lease Description [Table]
Geographical
Statement Geographical [Axis]
Geographical
Segment Geographical [Domain]
U.S. [Member]
UNITED STATES
Ireland [Member]
IRELAND
Lessee Lease Description [Line Items]
Lessee Lease Description [Line Items]
Lease Cost
Lease Cost [Abstract]
Operating lease cost
Operating Lease Cost
Financing lease cost
Financing Lease Cost
Sublease income
Sublease Income
Total
Lease Cost
Other information
Other Lease Information [Abstract]
Operating cash flows out from operating leases
Operating Lease Payments
Operating cash flows in from operating leases
Proceeds From Lease Payments
Operating cash flows out from financing leases
Finance Lease Principal Payment On Liability
Right-of-use assets exchanged for new operating lease liabilities
Weighted average remaining lease term
Operating Lease And Financing Lease Weighted Average Remaining Lease Term
Weighted average discount rate - operating leases
Operating Lease Weighted Average Discount Rate Percent
Year ended December 31, 2021
Lessee Operating Lease Liability Payments Due Next Twelve Months
Year ended December 31, 2022
Lessee Operating Lease Liability Payments Due Year Two
Year ended December 31, 2023
Lessee Operating Lease Liability Payments Due Year Three
Total
Lessee Operating Lease Liability Payments Due
Less present value discount
Lessee Operating Lease Liability Undiscounted Excess Amount
Operating lease liabilities included in the consolidated balance sheets at December 31, 2020
Operating Lease Liability
Equity Method Investments And Cost Method Investments [Abstract]
Equity Method Investments And Cost Method Investments [Abstract]
Debt Instrument [Table]
Debt Instrument [Table]
Pre-funded series D warrant.
Pre Funded Series D Warrant [Member]
Pre Funded Series D Warrant [Member]
Debt Instrument
Debt Instrument [Axis]
Debt Instrument, Name
Debt Instrument Name [Domain]
Senior secured promissory notes.
Senior Secured Promissory Notes [Member]
Senior Secured Promissory Notes [Member]
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Number of common shares issuable on cancellation of warrants
Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
Debt instrument, principal face amount
Debt Instrument Face Amount
Debt instrument maturity date
Debt Instrument Maturity Date
Interest rate
Debt Instrument Interest Rate Stated Percentage
Debt Instrument, issuance date
Debt Instrument Issuance Date1
Debt instrument, conversion price
Debt Instrument Convertible Conversion Price1
Long-term Debt, Type
Longterm Debt Type [Axis]
Long-term Debt, Type
Longterm Debt Type [Domain]
Convertible Notes Payable [Member]
Convertible Notes Payable [Member]
Eight point zero percentage july two thousand and nineteen notes.
8.0% July 2019 Notes [Member]
Eight Point Zero Percentage July Two Thousand And Nineteen Notes [Member]
Current interest rate
Principal
Stockholders equity note.
Stockholders equity note.
Stockholders Equity Note [Table]
Stockholders Equity Note [Table]
Series A Preferred Stock [Member]
Series A Preferred Stock [Member]
Series C Preferred Stock [Member]
Series B Preferred Stock [Member]
Series C Preferred Stock [Member]
Series C Preferred Stock [Member]
Series E convertible preferred stock.
Series E Convertible Preferred Stock [Member]
Series E Convertible Preferred Stock [Member]
Series E preferred stock and related warrants.
Series E Preferred Stock and Related Warrants [Member]
Series E Preferred Stock And Related Warrants [Member]
July two thousand nineteen private placement.
July Two Thousand Nineteen Private Placement
July Two Thousand Nineteen Private Placement [Member]
Transaction Type
Transaction Type [Axis]
Transaction
Transaction [Domain]
Securities purchase agreement.
Securities Purchase Agreement
Securities Purchase Agreement [Member]
Series E-1 convertible preferred stock.
Series E-1 Convertible Preferred Stock [Member]
Series E1 Convertible Preferred Stock [Member]
August two thousand nineteen private placement.
August 2019 Private Placement [Member]
August Two Thousand Nineteen Private Placement [Member]
Convertible Preferred Stock
Convertible Preferred Stock [Member]
Two thousand and nineteen warrants.
2019 Warrants [Member]
Two Thousand And Nineteen Warrants [Member]
Preferred Stock and Two Thousand and Nineteen Warrants.
Preferred Stock and 2019 Warrants [Member]
Preferred Stock And Two Thousand And Nineteen Warrants [Member]
Private placements and debt exchange.
Private Placements and Debt Exchange [Member]
Private Placements And Debt Exchange [Member]
Series D Preferred Shares [Member]
Stockholders Equity Note [Line Items]
Stockholders Equity Note [Line Items]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Plan Name
Plan Name [Axis]
Plan Name
Plan Name [Domain]
Two thousand and nineteen equity incentive plan.
2019 Equity Incentive Plan [Member]
Two Thousand And Nineteen Equity Incentive Plan [Member]
2020 Omnibus Equity Incentive Plan.
2020 Omnibus Equity Incentive Plan [Member]
Two Thousand Twenty Omnibus Equity Incentive Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of common shares reserved for issuance
Common Stock Capital Shares Reserved For Future Issuance
Stock options, exercise price of common stock granted as percentage of fair value on the date of grant
Sharebased Compensation Arrangement By Sharebased Payment Award Purchase Price Of Common Stock Percent
Number of common shares remained available to be issued.
Number of common shares remained available to be issued
Number Of Common Shares Remained Available To Be Issued
Additional common stock share issued.
Related Party
Related Party Transactions By Related Party [Axis]
Related Party
Related Party [Domain]
Canaccord Genuity LLC And Roth Capital Partner LLC
Canaccord Genuity L L C And Roth Capital Partner L L C
Canaccord Genuity L L C And Roth Capital Partner L L C [Member]
Additional common stock share issued
Additional Common Stock Share Issued
Shares issued, price per share
Shares Issued Price Per Share
Gross proceeds from issuance of common stock
Proceeds From Issuance Of Common Stock
Underwriting discount, commission and estimated offering expenses
Other Underwriting Expense
At-The-Market Offering, Aggregate Offering Price.
Percentage Of Commission On Aggregate Gross Proceeds.
Represents the amount of expense provided in the period for legal fees and disbursements.
Percentage On Sale Of Stock Consideration Received On Transaction.
Percentage Of Underwriting Fee To Be Received on company offerings.
Common stock offering period of restriction common stock.
Cantor fitzgerald and co [Member].
Cantor Fitzgerald & Co [Member]
Cantor Fitzgerald And Co [Member]
Roth Capital Partners, LLC.
Roth Capital Partners L L C
Roth Capital Partners L L C [Member]
Award Type
Award Type [Axis]
Award Type
Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain]
At-the-market offering, aggregate offering price
At The Market Offering Aggregate Offering Price
Percentage of commission on aggregate gross proceeds
Percentage Of Commission On Aggregate Gross Proceeds
Legal fees and disbursements
Legal Fees And Disbursements
Percentage of fee on gross sale price per share
Percentage On Sale Of Stock Consideration Received On Transaction
Percentage of underwriting fee to be received on company offerings
Percentage Of Underwriting Fee To Be Received By Related Party
Common stock offering period
Common Stock Offering Period Of Restriction Common Stock
Shares issued in public offering
Stock Issued During Period Shares New Issues
Warrants issued to purchase of common stock.
Series F warrants.
Series F warrants [Member]
Series F Warrants [Member]
Pre funded warrants member.
Pre-Funded Warrants [Member]
Pre Funded Warrants [Member]
Warrants issued to purchase of common stock
Warrants Issued To Purchase Of Common Stock
Warrant exercise price
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
Underwriting discounts and other offering expenses
Payments For Underwriting Expense
Debt and warrants exchanged for preferred stock.
Value of accounts payable exchanged.
Number of shares issued upon exchange of accounts payable.
Number of shares issued upon exchange of investor waiver rights.
Number of shares issued
Shares Issued
Debt and warrants exchanged for preferred stock
Debt And Warrants Exchanged For Preferred Stock
Number of preferred stock and warrants issued upon conversion
Conversion Of Stock Shares Issued1
Value of accounts payable exchanged
Value Of Accounts Payable Exchanged
Number of shares issued upon exchange of accounts payable
Number Of Shares Issued Upon Exchange Of Accounts Payable
Number of shares issued upon exchange of investor waiver rights
Number Of Shares Issued Upon Exchange Of Investor Waiver Rights
Net proceeds from issuance of preferred stock
Proceeds From Issuance Of Convertible Preferred Stock
Beneficial conversion feature
Debt Instrument Convertible Beneficial Conversion Feature
Warrant exercisible term.
Warrant exercisable term
Warrant Exercisible Term
Conversion of stock, description
Conversion Of Stock Description
Conversion of stock, shares issued
Convertible Preferred Stock Shares Issued Upon Conversion
Number of shares called upon exercise of warrant
Class Of Warrant Or Right Number Of Securities Called By Each Warrant Or Right
Conversion price and exercise price per share
Share Price
Registration cost of shares of common stock.
Registration cost of shares of common stock
Registration Cost Of Shares Of Common Stock
Estimated fair value of warrant reclassified from Derivative liability to equity.
Excess of the fair value of the common stock
Debt Instrument Convertible If Converted Value In Excess Of Principal
Deemed dividend for triggering of warrant down round feature
Warrant Down Round Feature Increase Decrease In Equity Amount
Estimated fair value of warrant reclassified from Derivative liability to equity
Estimated Fair Value Of Warrant Reclassified From Derivative Liability To Equity
Conversion of stock preferred shares converted
Conversion Of Stock Shares Converted1
Common stock grant date fair value
Equity Fair Value Disclosure
Stock Issued During Period Shares associated other warrants.
Exercise of pre-funded Series D Warrants (in shares)
Stock issued during period shares associated other warrants
Stock Issued During Period Shares Associated Other Warrants
Purchase of warrants.
Loss in exchange of common stock with warrants.
Purchase of warrants
Purchase Of Warrants
Weighted average exercise price
Sharebased Compensation Shares Authorized Under Stock Option Plans Exercise Price Range Exercisable Options Weighted Average Exercise Price1
Loss in exchange of common stock with warrants
Loss In Exchange Of Common Stock With Warrants
Preferred stock shares exchanged.
Issuance of senior secured promissory note in exchange of preferred stock.
Preferred stock shares exchanged
Preferred Stock Shares Exchanged
Preferred stock, aggregate stated value
Proceeds from exchange of senior secured promissory note
Proceeds From Issuance Of Secured Debt
Issuance of senior secured promissory note in exchange of preferred stock
Issuance Of Senior Secured Promissory Note In Exchange Of Preferred Stock
Grant date fair value of award.
Trading Activity
Trading Activity By Type [Axis]
Trading Activity, by Type
Trading Activity By Type [Domain]
one point five times closing price [member]
1.5 times closing trading price per share [Member]
One Point Five Times Closing Price [Member]
two point zero times the closing price [member]
2.0 times closing trading price per share [Member]
Two Point Zero Times Closing Price [Member]
Title of Individual
Title Of Individual [Axis]
Title of Individual
Title Of Individual With Relationship To Entity [Domain]
Chief Executive Officer [Member]
Chief Executive Officer [Member]
New employee.
New Employee [Member]
New Employee [Member]
Stock options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
Stock options vesting period
Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1
Stock options exercise price per share
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
Stock options vested
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Number
Stock options outstanding to vest
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
Grant date fair value of award
Grant Date Fair Value Of Award
Weighted Average Remaining Contractual Term (Years), Exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
Expected terms (years)
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
Expected volatility
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
Risk-free interest rate, minimum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
Risk-free interest rate, maximum
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
Expected dividends
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
Weighted average estimated fair value of the stock options granted
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
Number of Shares, Outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
Number of Shares, Granted
Number of Shares, Exercised
Stock Issued During Period Shares Stock Options Exercised
Number of Shares, Cancelled/Forfeited
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
Number of Shares, Outstanding
Number of Shares, Exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
Weighted Average Exercise Price, Outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
Weighted Average Exercise Price, Granted
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
Weighted Average Exercise Price, Cancelled/Forfeited
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
Weighted Average Exercise Price, Outstanding
Weighted Average Exercise Price, Exercisable
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
Weighted Average Remaining Contractual Term (Years), Outstanding
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
Aggregate Intrinsic Value, Outstanding
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
Aggregate Intrinsic Value, Exercisable
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
Exercise Price Range
Share Based Compensation Shares Authorized Under Stock Option Plans By Exercise Price Range [Axis]
Exercise Price Range
Share Based Compensation Shares Authorized Under Stock Option Plans Exercise Price Range [Domain]
Exercise price range from ten to fifteen.
$10 - $15 [Member]
Exercise Price Range From Ten To Fifteen [Member]
Exercise price range from fifteen to twenty.
$15 - $20 [Member]
Exercise Price Range From Fifteen To Twenty [Member]
Exercise price range from twenty to twenty five.
$20 - $25 [Member]
Exercise Price Range From Twenty To Twenty Five [Member]
Exercise price range above twenty five.
+ $25 [Member]
Exercise Price Range Above Twenty Five [Member]
Outstanding Number of Options
Share-based compensation (Income) expense.
Unrecognized compensation expense related to non-vested share-based compensation awards
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
Cost expected to be recognized over weighted average period
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
Share-based compensation (Income) expense
Share Based Compensation Income Expense
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Income Statement Location
Income Statement Location [Axis]
Income Statement Location
Income Statement Location [Domain]
Selling, General and Administrative [Member]
Selling General And Administrative Expenses [Member]
Research and Development [Member]
Research And Development Expense [Member]
Cost of Goods Sold [Member]
Cost Of Sales [Member]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
The number of each class of warrants or rights issued during the period.
The number of each class of warrants or rights exercised during the period.
The number of each class of warrants or rights that expired during the period.
A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.
Class of warrant or right exercisable.
Warrants outstanding [Roll Forward]
Warrants Outstanding Roll Forward
Outstanding, beginning of period (in shares)
Class Of Warrant Or Right Outstanding
Warrants issued (in shares)
Class Of Warrant Or Right Issued
Warrants exercised (in shares)
Class Of Warrant Or Right Exercises In Period
Warrants expired (in shares)
Class Of Warrant Or Right Expired In Period
Warrants exchanged (in shares)
Outstanding, end of period (in shares)
Exercisable, end of period (in shares)
Class Of Warrant Or Right Exercisable
Weighted average exercise price for the number of warrants or rights issued for the unvested, forfeitable warrants or rights in period.
Weighted average exercise price for warrants or rights to acquire and convert their warrants into shares that were exercised during the period.
Weighted average exercise price per share for warrants or rights for securities that expired in period.
A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.
Weighted average exercise price for warrants or rights outstanding.
Class of warrant or right exercisable weighted average exercise price.
Warrants, Exercise Price per Share [Roll Forward]
Class Of Warrant Or Right Weighted Average Exercise Price Roll Forward
Outstanding, beginning of period (in dollars per share)
Class Of Warrant Or Right Weighted Average Exercise Price
Warrants issued (in dollars per share)
Class Of Warrant Or Right Weighted Average Exercise Price Issued
Warrants exercised (in dollars per share)
Class Of Warrant Or Right Weighted Average Exercise Price Exercises In Period
Warrants expired (in dollars per share)
Class Of Warrant Or Right Weighted Average Exercise Price Expirations In Period
Outstanding, ending of period (in dollars per share)
Exercisable, (in dollars per share)
Class Of Warrant Or Right Exercisable Weighted Average Exercise Price
Weighted average remaining contractual term for each class of warrants or rights outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
Class of warrant or right exercisable weighted average remaining contractual term.
Weighted average remaining life
Class Of Warrant Or Right Weighted Average Remaining Contractual Term
Weighted average remaining life, Exercisable
Class Of Warrant Or Right Exercisable Weighted Average Remaining Contractual Term
Class of warrant or right outstanding intrinsic value.
Class of warrant or right exercisable intrinsic value.
Aggregate Intrinsic Value, Outstanding
Class Of Warrant Or Right Outstanding Intrinsic Value
Aggregate Intrinsic Value, Exercisable
Class Of Warrant Or Right Exercisable Intrinsic Value
Class Of Warrant Or Right [Table]
Class Of Warrant Or Right [Table]
Range of exercise prices Point zero one range.
$0.01 [Member]
Range Of Exercise Prices Point Zero One Range [Member]
Range of exercise prices Ten point zero range.
$10.00 [Member]
Range Of Exercise Prices Ten Point Zero Range [Member]
Class Of Warrant Or Right [Line Items]
Class Of Warrant Or Right [Line Items]
Warrants Outstanding, Number Outstanding
Warrants Exercisable, Number Exercisable
Prefunded warrant.
Prefunded Warrant [Member]
Prefunded Warrant [Member]
Fair value measurement with unobservable inputs reconciliation recurring basis reclassified from liability to equity.
Beginning balance
Fair Value Measurement With Unobservable Inputs Reconciliations Recurring Basis Liability Value
Total change in the liability included in earnings
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Gain Loss Included In Earnings
Reclass from liability to equity
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Reclassified From Liability To Equity
Fair value of warrants issued
Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Issues
Ending balance
February two thousand eighteen warrants.
Febuary 2018 Warrants [Member]
February Two Thousand Eighteen Warrants [Member]
Number of warrants outstanding (in shares)
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Measurement Input Type
Measurement Input Type [Axis]
Measurement Input Type
Measurement Input Type [Domain]
Contractual Term [Member]
Measurement Input Expected Term [Member]
Expected Volatility [Member]
Measurement Input Price Volatility [Member]
Risk-free Interest Rates [Member]
Measurement Input Risk Free Interest Rate [Member]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Warrants expiration period
Warrants And Rights Outstanding Term
Warrants measurement input
Warrants And Rights Outstanding Measurement Input
Liability Class
Fair Value By Liability Class [Axis]
Fair Value by Liability Class
Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation By Liability Class [Domain]
Derivative Instruments Liabilities [Member]
Derivative Financial Instruments Liabilities [Member]
Measurement Frequency
Fair Value By Measurement Frequency [Axis]
Measurement Frequency
Fair Value Measurement Frequency [Domain]
Recurring [Member]
Fair Value Measurements Recurring [Member]
Fair Value Hierarchy and NAV
Fair Value By Fair Value Hierarchy Level [Axis]
Fair Value Hierarchy and NAV
Fair Value Measurements Fair Value Hierarchy [Domain]
Fair Value, Inputs, Level 1
Fair Value Inputs Level1 [Member]
Level 2 [Member]
Fair Value Inputs Level2 [Member]
Level 3 [Member]
Fair Value Inputs Level3 [Member]
Liabilities [Abstract]
Liabilities Fair Value Disclosure [Abstract]
Total Liabilities
Liabilities Fair Value Disclosure
Reimbursement for travel and stay.
Commitments And Contingencies Disclosure [Abstract]
Loss Contingencies [Table]
Loss Contingencies [Table]
Litigation Status
Litigation Status [Axis]
Litigation Status
Litigation Status [Domain]
Pending Litigation [Member]
Pending Litigation [Member]
Lease Contractual Term
Lease Contractual Term [Axis]
Lease Contractual Term
Lease Contractual Term [Domain]
Two thousand fifteen sublease agreement.
Sublease 2015 [Member]
Two Thousand Fifteen Sublease Agreement [Member]
Two thousand twenty one Sublease agreement.
2021 Sub-Lease Agreement [Member]
Two Thousand Twenty One Sublease Agreement [Member]
Office space at 1633 Broadway, New York, NY.
Office Space at 1301 Avenue of the Americas, New York, NY [Member]
Office Space At1633 Broadway New York N Y [Member]
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Unpaid compensation amounts claimed
Loss Contingency Damages Sought Value
Accrued unpaid compensation amounts
Loss Contingency Accrual At Carrying Value
Salary and wage, Officer
Officers Compensation
Annual target cash bonus, (in percent)
Deferred Compensation Arrangement With Individual Cash Awards Granted Percentage
Reimbursement for travel and stay, per month
Reimbursement For Travel And Stay
Employment agreement, description
Deferred Compensation Arrangement With Individual Description
Increase in lease rent expenses.
Lease, description
Lessor Operating Lease Description
Additional area of space
Area Of Land
Increase in sublease rent
Increase In Lease Rent Expenses
Extension of sublease
Lessor Operating Lease Option To Extend
Sublease rent
Lease And Rental Expense
Operating or finance lease
Sub lease expiration date
Lease Expiration Date1
Operating lease liability future minimum sublease rentals.
Operating lease liability future minimum sublease rentals due next twelve months.
Operating lease liability future minimum sublease rentals due year two.
Operating lease liability future minimum sublease rentals due.
Future minimum lease payments under all operating leases [Abstract]
Operating Lease Liability Future Minimum Sublease Rentals [Abstract]
2021
Operating Lease Liability Future Minimum Sublease Rentals Due Next Twelve Months
2022
Operating Lease Liability Future Minimum Sublease Rentals Due Year Two
2023
Operating Lease Liability Future Minimum Sublease Rentals Due
Rent expense, net of receipts under the terms of subleases
Operating Leases Rent Expense Net
Minimum letter of credit amount required to be maintained under lease agreement.
Letter of credit
Letter Of Credit [Abstract]
Minimum letter of credit amount required to be maintained under lease agreement
Minimum Letter Of Credit Amount Required To Be Maintained
Expiration date of letter of credit
Line Of Credit Facility Expiration Date1
Operating Loss Carryforwards [Table]
Operating Loss Carryforwards [Table]
Income Tax Authority
Income Tax Authority [Axis]
Income Tax Authority
Income Tax Authority [Domain]
Federal [Member]
Domestic Country [Member]
State and City [Member]
State And Local Jurisdiction [Member]
Foreign [Member]
Foreign Country [Member]
Tax Credit Carryforward
Tax Credit Carryforward [Axis]
Tax Credit Carryforward, Name
Tax Credit Carryforward Name [Domain]
Research and Development Tax Credit Carryforwards [Member]
Research [Member]
Tax Period
Tax Period [Axis]
Tax Period
Tax Period [Domain]
Expire between 2019 and 2037.
Expire Between 2019 and 2037 [Member]
Expire Between2019 And2037 [Member]
Earliest Tax Year [Member]
Earliest Tax Year [Member]
Latest Tax Year [Member]
Latest Tax Year [Member]
Income Tax Authority, Name
Income Tax Authority Name [Axis]
Income Tax Authority, Name
Income Tax Authority Name [Domain]
New York State [Member]
New York State Division Of Taxation And Finance [Member]
New York City.
New York City [Member]
New York City [Member]
Domestic and state tax authority.
Federal and State [Member]
Domestic And State Tax Authority [Member]
Operating Loss Carryforwards [Line Items]
Operating Loss Carryforwards [Line Items]
Income tax expense
Income Tax Expense Benefit
Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments [Abstract]
Domestic
Income Loss From Continuing Operations Before Income Taxes Domestic
Foreign
Income Loss From Continuing Operations Before Income Taxes Foreign
Income (loss) before taxes
Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments
Income tax reconciliation, nondeductible expense, interest.
Income tax reconciliation loss on extinguishment of debt.
Income tax rate reconciliation state operating loss carryforwards.
Income tax reconciliation, federal tax credits.
Income tax reconciliation branch income
Valuation allowance deferred tax asset change in amount charged to costs and expenses.
The portion of the difference between total income tax expense or benefit as reported in the Income Statement and the expected income tax expense or benefit computed by applying the domestic federal statutory income tax rates to pretax income from continuing operations attributable to derivative costs.
Provision for income taxes [Abstract]
Income Tax Expense Benefit Continuing Operations Income Tax Reconciliation [Abstract]
Income taxes using U.S federal statutory rate
Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
Nondeductible interest
Income Tax Reconciliation Nondeductible Expense Interest
Loss on extinguishment of debt
Income Tax Reconciliation Loss On Extinguishment Of Debt
Loss of tax benefit of state net operating loss carryforwards
Income Tax Rate Reconciliation State Operating Loss Carryforwards
Loss of tax benefit of federal tax credit carryforwards
Income Tax Reconciliation Federal Tax Credits
Branch income
Income Tax Reconciliation Branch Income
State income taxes, net of federal benefit
Income Tax Reconciliation State And Local Income Taxes
Foreign rate differential
Income Tax Reconciliation Foreign Income Tax Rate Differential
Valuation allowance
Valuation Allowance Deferred Tax Asset Change In Amount Charged To Costs And Expenses
Derivative charge
Income Tax Reconciliation Derivative Charge
Stock option exercises and cancellations
Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
Research and development costs
Income Tax Reconciliation Nondeductible Expense Research And Development
Other
Income Tax Reconciliation Other Reconciling Items
Total
Deferred tax assets lease obligations.
Deferred tax liabilities right of use asset.
Deferred tax assets:
Deferred Tax Assets Net [Abstract]
Employee compensation accruals
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Employee Compensation
Accrued liabilities
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Accrued Liabilities
Research tax credits
Deferred Tax Assets Tax Credit Carryforwards Research
Lease obligation
Deferred Tax Assets Lease Obligations
Other
Deferred Tax Assets Other
Net operating losses
Deferred Tax Assets Operating Loss Carryforwards
Total deferred tax assets
Deferred Tax Assets Gross
Deferred tax liabilities:
Deferred Tax Liabilities [Abstract]
Right of use asset
Deferred Tax Liabilities Right Of Use Asset
Total deferred tax liabilities
Deferred Income Tax Liabilities
Valuation allowance
Deferred Tax Assets Valuation Allowance
Net deferred tax assets
Deferred Tax Assets Liabilities Net
The amount of annual limitations on the use of all operating loss carryforwards available to reduce future taxable income.
Operating loss carryforwards net expected to expire unutilized and unavailable to offset future federal taxable income.
Operating loss carryforwards available for offsetting against future taxable income.
Operating loss carry forwards expiration year.
Tax credit carry forward expiration year.
Operating loss carryforwards not subject to expiration.
Tax credit carryforwards expected to expire unutilized.
Operating loss carryforwards
Operating Loss Carryforwards
Operating loss carryforwards, annual limitation
Operating Loss Carryforwards Annual Limitations
Operating loss carryforwards net, expected to expire unutilized and unavailable to offset future federal taxable income
Operating Loss Carryforwards Net Expected To Expire Unutilized And Unavailable To Offset Future Federal Taxable Income
Operating loss carryforwards available for offset future taxable income
Operating Loss Carryforwards Available For Offsetting Against Future Taxable Income
Operating loss carryforwards for unlimited period
Operating Loss Carryforwards Not Subject To Expiration
Operating loss carryforwards, expiration dates
Operating Loss Carry Forwards Expiration Year
Tax credit carryforwards
Tax Credit Carryforward Amount
Tax credit carryforwards, expiration dates
Tax Credit Carry Forward Expiration Year
Tax credit carryforwards expected to expire unutilized
Tax Credit Carryforwards Expected To Expire Unutilized
The percentage of the amount of valuation allowance to deferred tax asset.
Percentage of valuation allowance against deferred tax assets
Valuation Allowance Deferred Tax Asset Percentage
Decrease in deferred tax assets valuation allowance
Valuation Allowance Deferred Tax Asset Change In Amount
Valuation allowance deferred tax asset change in amount charged to additional paid in capital.
Valuation allowance deferred tax asset change in amount charged to retained earnings.
Valuation allowance deferred tax asset change in amount charged to other comprehensive income.
Beginning balance
Charged to costs and expenses
Charged to additional paid-in capital
Valuation Allowance Deferred Tax Asset Change In Amount Charged To Additional Paid In Capital
Charged to retained earnings
Valuation Allowance Deferred Tax Asset Change In Amount Charged To Retained Earnings
Charged to other comprehensive income
Valuation Allowance Deferred Tax Asset Change In Amount Charged To Other Comprehensive Income
Ending balance
Open tax period.
Open tax period
Open Tax Period
Subsequent Event [Table]
Subsequent Event [Table]
Subsequent Event Type
Subsequent Event Type [Axis]
Subsequent Event Type
Subsequent Event Type [Domain]
Subsequent Event [Member]
Subsequent Event [Member]
Series E and E1 convertible preferred stock member.
Series E And E1 Convertible Preferred Stock
Series E And E1 Convertible Preferred Stock [Member]
Stock Warrant Exercises [Member]
Warrant [Member]
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Stock issued during period shares cashless exercise of warrants.
Warrants issued to purchase of common stock
Stock issued during period, cashless exercise of Series E warrants
Stock Issued During Period Shares Cashless Exercise Of Warrants
Issue of unregistered common stock for advisory services
Issue of unregistered common stock for advisory services
Issue Of Unregistered Common Stock For Advisory Services